Athens LifeTech Park (ALTP) is an emerging life sciences innovation hub based in Athens, Greece, with the mission to advance early-stage drug discovery and development research, for the benefit of patients worldwide. To fulfill this mission, we provide high-quality preclinical contract research services tailored to the needs of our clients. With a dedicated and highly skilled team, cutting-edge infrastructure, and competitive operational costs, ALTP is the ideal partner for life sciences companies and academic institutions seeking reliable and high-quality preclinical research solutions.
About Us
Our team of experienced scientists, veterinarians, and research professionals is dedicated to delivering precise, high-quality data and customized research solutions. Specializing in a broad range of preclinical disciplines, we ensure that every aspect of your research is conducted with accuracy and care. Quality is at the core of everything we do. Our rigorous methodologies and adherence to internationally recognized standards ensure the reliability and reproducibility of our research. Operating within the European Union, we strictly comply with EU regulatory frameworks, upholding the highest ethical and scientific standards necessary for global drug development.
ALTP: Collaboration That Delivers
- Proximity to Athens International Airport
- Dual Corridor Vivarium with Multiple suites, procedure rooms, breeding rooms, Necropsy room
- Bioanalytical, Biotechnology, In vitro, In vivo, ex vivo labs, Auxiliary labs & Tissue Culture labs under one roof
- ISO 9001:2015 certified (IAS, US & ESYD, National Certification)
- Soon to be AAALAC accredited
- Mmultidisciplinary team of PhD experts > 15-20 years of experience (Academia and Industry)
- Veterinarians & Technicians with FELASA A, B, C & D certified
ALTP Preclinical Research Services
Mini Pig and Swine PK Capabilities: Advancing Preclinical Research
At the forefront of preclinical research, mini pigs and swine provide an exceptional model for studying drug pharmacokinetics (PK) due to their notable physiological and anatomical similarities to humans, making them an ideal model for evaluating absorption, distribution, metabolism, and excretion (ADME) properties of drug candidates. Leveraging these attributes, we offer a specialized suite of services designed to optimize PK studies and accelerate drug development.
Comprehensive Capabilities
Our dedicated mini pig and swine PK platform provides end-to-end support for your drug development needs:
- PK/ADME Studies: Full characterization of drug pharmacokinetics.
- Single & multiple dose studies: Oral, intravenous (IV), intraperitoneal (IP), and other client-specified methods.
- Surgical Expertise: Advanced surgical techniques for catheterization, sampling, and dosing. Jugular vein, portal vein, or bile duct cannulation available to support complex PK studies.
Specialized Services
- Dermal and Transdermal PK.
- Neonatal and Juvenile Models
- Disease Models
Routine & Specialized PK Capabilities Across Diverse Species
- Rodent Models: Mice & Rats
- Single or multiple-dose regimens: Oral, intravenous (IV), intraperitoneal (IP), and other client-specified methods.
- Study setup: Typically includes 2–6 animals per sex per dose group and 5–10 sampling time points (or customized configurations based on client requirements).
- Tissue Distribution Studies
- PK Studies in Cannulated Rats
- Cassette Dose PK Studies
- Effect of Food on Pharmacokinetics
- Effect of Gender Differences on Pharmacokinetics
Bioanalytical Services
Our Bioanalytical Services support drug development through precise quantification, characterization, and analysis of pharmaceutical compounds. We provide end-to-end solutions tailored to meet regulatory and scientific needs.
Method Development & Validation
- Full Method Development
- Partial Method Development
- Fit-to-Purpose Method Development
High-Throughput ADME Screening Assay Methods
- Advanced techniques for rapid screening of multiple compounds, designed for speed and efficiency without compromising data quality.
- Analysis of Screening assays to assess Absorption, Distribution, Metabolism, and Excretion (ADME) properties including permeability studies, metabolic stability, hepatocyte stability and protein binding assays.
In vitro Studies
At ALTP, our in vitro research capabilities form the foundation of translational success. Designed for precision, scalability, and scientific depth, our platform supports early-stage discovery through to IND-enabling studies.
- Plasma Stability
- RBC Partitioning
- Permeability Assays
- Protein Binding
- Metabolic Stability
- Reaction Phenotyping
- Hepatocyte stability
- ATP content Assay
- MTT Assay
- Caspase Assay
- Apoptosis Assay
Toxicology Services
Comprehensive safety assessment studies, including acute, sub-chronic, and chronic toxicity evaluations. We combine scientific rigor with operational precision to deliver high-quality, reproducible data that informs go/no-go decisions and accelerates clinical translation.
- DRF studies
- Acute Toxicity
- Sub-acute Toxicity (7, 14, 28 & 90 day)
- Sub-chronic Toxicity
- Toxicokinetics
- Repeated Dose Toxicity Studies in Rodents (rats/mice) and Non-Rodents (Mini pigs and Swine)
Pharmacology Services
- Tailored efficacy and mechanism-of-action studies to support drug discovery and development. ALTP offers a robust pharmacology platform designed to generate high-quality, decision-enabling data across therapeutic areas.
- Efficacy Studies in Rodent Models: Dermatology, Oncology, inflammation, and metabolic disease models
- Dose-Response & Time-Course Evaluations: Quantitative assessment of pharmacokinetic and pharmacodynamic endpoints
- Target Engagement & Biomarker Analysis: qPCR, ELISA and LC-MS/MS-based quantification
Biotechnology Services
- At ALTP, our biotechnology platform is designed to support cutting-edge research, therapeutic innovation, and translational development. We offer a suite of advanced capabilities that empower clients to explore complex biological systems, validate novel targets, and accelerate preclinical breakthroughs.
- Organoid & 3D Tissue Culture Systems: Disease-relevant models for oncology, immunology, and regenerative medicine
- Custom Assay Development: Tailored protocols for cytotoxicity, apoptosis, mitochondrial function, and biomarker quantification
- Mitochondrial Biology Platforms: ATP content, caspase activation, mtCO1 and mtND1 expression profiling via qPCR
Our Flexible Preclinical Collaboration Models
We understand that every research project is unique. That’s why we offer adaptable collaboration models to meet the diverse needs of our clients. Whether you require comprehensive support or targeted expertise, we are here to ensure your project succeeds.
- Full-Service, End-to-End Project Management
- Individualized Support for Specific Research Phases
- Partnership Opportunities
Why Partner with Us?
- Expertise: A multidisciplinary team with decades of experience in preclinical research & species-specific knowledge.
- Comprehensive Services: End-to-end support or phase-specific assistance, customized to your needs.
- State-of-the-Art Facilities: Advanced labs and equipment to ensure precise and reliable results.
- Speed, Efficiency & Flexibility: Scalable and adaptable collaboration models & Streamlined workflows to deliver results on time.
Your Vision, Our Expertise Whether you’re a biotech startup, pharmaceutical company, or academic researcher, we are committed to delivering preclinical solutions that align with your vision. By partnering with us, you gain a reliable ally dedicated to advancing your research and ensuring your success.
ALTP Preclinical CRO: Your trusted Partner in Preclinical Success
We are here for you as a dedicated partner and a true extension of your research team, committed to providing the expertise, data, and support to turn your vision into reality.